# Furosemide for Dogs: Dosage, Uses, and Side Effects Furosemide is a prescription loop diuretic that makes a dog urinate off excess sodium and water. Veterinarians use it most often to clear fluid from the lungs and body in congestive heart failure, and sometimes to manage edema from other causes. It is a fast-acting drug that can relieve life-threatening breathing difficulty within hours, which is why it sits at the center of emergency heart failure treatment in dogs [1]. It is not a cure for heart disease. It controls the fluid buildup that heart disease produces, and it must be paired with other medications and close monitoring to be used safely. This guide covers how furosemide works, the label-sourced dose ranges, how it is given by mouth and by injection, the electrolyte and kidney problems it can cause, and what owners need to watch at home. Every dose figure below comes from the drug label or a cited veterinary source. Nothing here replaces an examination by your dog's veterinarian. This article is educational and is not a substitute for veterinary diagnosis or treatment. ## At a Glance | Feature | Detail | |--|--| | Active ingredient | Furosemide (loop diuretic) | | Brand names | Lasix and generic equivalents | | Species | Dogs (also used in cats under veterinary direction) | | How it is given | By mouth as tablets or oral solution, or by injection under the skin, into a muscle, or into a vein | | How fast it works | Injectable forms act within minutes. Oral forms begin working within about an hour | | How long it lasts | Roughly 6 to 8 hours per dose, which is why most dogs are dosed every 8 to 12 hours | | Prescription status | Prescription only in the United States. Not available over the counter | | Main use | Congestive heart failure with pulmonary edema or body cavity effusion | | Key risks | Dehydration, low potassium, low sodium, kidney injury, hearing damage with rapid IV injection | ## What Furosemide Is and What It Treats Furosemide belongs to the loop diuretic class, named for the part of the kidney tubule where it acts, the loop of Henle. The Merck Veterinary Manual lists furosemide among the diuretics used in animals for edema and congestive heart failure [1]. In dogs, the two dominant uses are: - **Left-sided congestive heart failure**, where fluid backs up into the lungs and causes pulmonary edema. This is the classic emergency presentation, and it is the setting where furosemide saves lives fastest [2][3][4]. - **Right-sided congestive heart failure and other edema**, where fluid accumulates in the abdomen as ascites, in the chest as pleural effusion, or in the tissues as peripheral edema. Myxomatous mitral valve disease is the most common cause of left-sided congestive heart failure in dogs, and it is the condition studied in most of the recent furosemide research [4][5][6][7]. Dilated cardiomyopathy is another common cause, and dogs with that diagnosis often need diuretics as part of a multi-drug regimen [8][9]. Furosemide is also used in some non-cardiac fluid states, but the evidence base for those uses is thinner. The label and the veterinary literature focus on heart failure and edema. ### What Furosemide Does Not Do Furosemide does not treat the underlying heart disease. It does not repair a leaking valve, strengthen the heart muscle, or reverse the hormonal changes that drive heart failure. It removes fluid. That distinction matters because owners sometimes assume a dog on furosemide is "cured" once breathing normalizes. The dog still has heart disease, and the diuretic dose usually needs to be adjusted over time as the disease progresses [6][9]. Furosemide is also not a treatment for kidney failure, and in fact it can worsen kidney function in some dogs [3]. It is not a weight-loss drug. It is not appropriate for mild or preclinical heart disease that has not yet produced congestion. ## How Furosemide Works Furosemide blocks the sodium-potassium-chloride cotransporter in the thick ascending limb of the loop of Henle. By blocking sodium reabsorption at that site, it forces a large amount of sodium, and water with it, to stay in the urine. This is why the drug is called a high-ceiling diuretic: the dose can be pushed quite high before the effect plateaus. The clinical consequence is natriuresis, the loss of sodium in urine. Veterinary cardiologists now frame diuretic success in terms of natriuresis rather than just urine volume, because sodium handling is what determines whether congestion actually clears [10]. A dog that produces a lot of urine but retains sodium is not truly decongesting. Two studies make this concrete. In dogs with acute congestive heart failure, urine sodium concentration measured after an intravenous furosemide dose correlated with how long the dog needed supplemental oxygen. Dogs with a urine sodium below 87 mmol/L needed oxygen for about 24 hours, versus about 17 hours for dogs above that threshold, and they were less likely to come off oxygen successfully at 24 and 36 hours [2]. A separate study of dogs with acute left-sided heart failure from mitral valve disease found that higher urine sodium and a higher urine sodium-to-potassium ratio were linked to greater improvement on lung X-rays and shorter hospital stays. Dogs that survived to discharge had a higher urine sodium-to-potassium ratio than dogs that died in the hospital [5]. The practical takeaway is that furosemide responsiveness varies a lot between dogs. Some dogs clear fluid easily on a low dose. Others are resistant and need higher doses or a different route of administration [11][10]. ```mermaid flowchart TD A[Dog shows fluid buildup] --> B[Veterinarian examines and images chest] B --> C{Congestion confirmed} C -->|Yes| D[Start furosemide at label dose] C -->|No| E[Investigate other causes] D --> F[Recheck breathing rate and effort] F --> G[Check electrolytes and kidney values] G --> H{Fluid clearing and labs stable} H -->|Yes| I[Continue and taper to lowest effective dose] H -->|No| J[Adjust dose or route and recheck sooner] J --> G ``` ## Furosemide Dosage for Dogs Dose depends on the indication, the route, and how the individual dog responds. The label-sourced ranges below are the standard starting points. Your veterinarian will set the actual dose. | Indication | Typical Route | Label-Sourced Dose Range | Typical Frequency | Monitoring Frequency | |--|--|--|--|--| | Acute congestive heart failure with pulmonary edema | IV or IM initially, then PO | 1 to 2 mg/kg IV, IM, or SC. Transition to 1 to 4 mg/kg PO | Every 8 to 12 hours | Continuous during hospitalization, then electrolytes and renal values within 24 to 48 hours of any dose change | | Chronic congestive heart failure | PO | 1 to 4 mg/kg PO | Every 8 to 12 hours | Recheck electrolytes, BUN, and creatinine at 5 to 7 days after starting or changing dose, then every 3 to 6 months when stable | | Ascites or pleural effusion from right-sided heart failure | PO, or SC if oral absorption is poor | 1 to 4 mg/kg PO. SC dosing used when oral response is unsatisfactory | Every 8 to 12 hours | Body weight and abdominal girth at each visit. Electrolytes and renal values at 5 to 7 days, then every 3 to 6 months | | Refractory congestion despite oral diuretics | SC | Subcutaneous furosemide used as an alternative when oral therapy fails | Per veterinarian, typically every 8 to 12 hours | Electrolytes and renal values weekly until stable, then monthly | The 1 to 2 mg/kg injectable range and the 1 to 4 mg/kg oral range come from the drug label and are the figures most veterinarians start from. Do not adjust the dose on your own. Do not give a second dose because the first one "did not seem to work." Furosemide has a narrow margin between effective and excessive, and doubling a dose can cause dehydration or kidney injury within a day. ### Dose Escalation Over Time Heart failure is progressive, and furosemide doses tend to rise. One retrospective study of dogs with mitral valve disease and heart failure found that the initial furosemide dose was negatively associated with survival, meaning dogs started on higher doses had shorter survival times [9]. That does not mean high doses cause death. It means dogs that need high doses have more severe disease. Another study found that the daily oral furosemide dose was a predictor of congestive signs returning within 180 days in dogs with stable stage C mitral valve disease [6]. Again, this reflects disease severity more than drug harm. A clinical trial of 569 dogs with heart failure from mitral valve disease used a furosemide dose above 8 mg/kg per day as one definition of treatment failure [12]. That figure is a study endpoint, not a target dose. It tells you that veterinarians consider a daily dose above 8 mg/kg per day to be a sign that the dog is not doing well on standard therapy. ### Subcutaneous Furosemide When oral diuretics stop working well, often because fluid in the gut wall reduces drug absorption, subcutaneous furosemide becomes an option. A 2025 study of 13 dogs and 17 cats with refractory heart failure found that subcutaneous furosemide controlled breathing rate and effort in all cases, and owners were satisfied with the approach. Median survival after starting subcutaneous furosemide was 106 days in dogs [13]. This route is offered when owners are considering euthanasia because oral therapy has failed. It is not a first-line option, and it requires a veterinarian to teach the injection technique and set the dose. ### Continuous Rate Infusion Versus Intermittent Bolus In hospitalized dogs, furosemide can be given as repeated intravenous boluses or as a continuous rate infusion. A retrospective study of 100 pets with acute left-sided heart failure compared the two approaches. The median dose in the continuous infusion group was lower than in the bolus group, and respiratory rates improved in both. Creatinine and total plasma protein rose more in the continuous infusion group, suggesting a higher risk of dehydration and azotemia with that method [14]. The choice between them is a hospital decision based on the individual dog. ## How to Give Furosemide to Your Dog Furosemide is usually given by mouth at home as a tablet or oral solution. A few practical points: - **Give with or without food.** Food does not meaningfully change absorption, but giving the tablet in a small treat or pill pocket reduces spit-out. - **Time the doses evenly.** Every 8 to 12 hours means roughly morning, late afternoon, and bedtime if you are on three times daily. Even spacing keeps a steady diuretic effect and reduces the peaks that cause urgent urination. - **Expect frequent urination for 6 to 8 hours after each dose.** Plan walks accordingly. A dog that was previously housetrained may have accidents during the first week of therapy. This is the drug working, not a behavior problem. - **Never skip a dose because the dog seems fine.** Furosemide controls fluid, it does not cure the disease. Skipping doses allows fluid to reaccumulate, sometimes within 24 hours. - **If you miss a dose, give it when you remember unless it is almost time for the next one.** Do not double up. - **Keep water available at all times.** Do not restrict water unless your veterinarian specifically instructs you to. Restricting water while on a diuretic can cause dangerous dehydration. - **Weigh your dog weekly on the same scale.** A sudden weight gain of more than a pound or two suggests fluid is returning. A sudden weight loss suggests over-diuresis. - **Count the resting breathing rate.** When the dog is asleep, count breaths for 15 seconds and multiply by four. A sustained rate above 30 breaths per minute is a reason to call your veterinarian. ### Storage and Handling Store tablets at room temperature, away from moisture and direct light. Furosemide tablets can discolor with age, which is normal, but do not use tablets that are crumbling or have a strong new odor. Oral solutions should be kept as directed on the label. Wash your hands after handling the medication, and keep it out of reach of children and pets. ## Side Effects of Furosemide in Dogs Most side effects are direct consequences of losing too much fluid and too many electrolytes. They range from mild and expected to serious and requiring immediate veterinary attention. ### Common and Expected Effects - Increased urination, sometimes urgent - Increased thirst - Mild restlessness or pacing in the hours after a dose - Occasional vomiting or diarrhea, especially if the tablet is given on an empty stomach These effects usually settle within a week as the body adjusts. If they persist or worsen, call your veterinarian. ### Electrolyte Disturbances This is the most important category to understand. Furosemide forces sodium, potassium, and chloride out in the urine, and it can disturb all three. **Low potassium (hypokalemia).** In a study of normal dogs given furosemide with a sodium-restricted diet, three of six dogs had at least one serum potassium above the reference range during four weeks of observation [15]. The direction of that finding is worth reading carefully: furosemide plus a low-sodium diet shifted potassium in some dogs, and the study authors monitored it closely because potassium balance is fragile on diuretics. In dogs with heart failure, potassium can go either way depending on other medications and kidney function. **Low sodium (hyponatremia).** Excessive sodium loss can drop serum sodium. This can cause lethargy, confusion, and in severe cases neurologic signs. **Low chloride (hypochloremia).** A study of 46 dogs and 34 cats with acute heart failure found hypochloremia in 24 percent of cases, making it the most common electrolyte abnormality on admission. In dogs, serum chloride at admission was negatively correlated with furosemide dose at discharge and at end-stage heart failure [16]. Low chloride is a marker of more aggressive diuretic therapy and more advanced disease. ### Kidney Injury Furosemide reduces blood flow to the kidney by lowering circulating volume. In a study of 79 dogs receiving parenteral furosemide for left-sided heart failure, kidney injury developed in 38 dogs, or 48 percent. Most cases occurred during hospitalization. Injury was grade I in 25 dogs, grade II in 9, and grade III in 4. Higher blood pressure was associated with acute kidney injury during hospitalization, and a higher oral furosemide dose was associated with kidney injury after discharge. Baseline creatinine and use of a continuous infusion were not associated with increased risk. Kidney injury was not linked to long-term outcome, and of 13 dogs with grade II or III injury, azotemia reversed in 9 [3]. That last point matters. Furosemide-associated azotemia is often reversible when the dose is reduced or fluid balance is corrected. It is not automatically a reason to stop the drug forever, but it is a reason to recheck labs promptly. ### Dehydration Dehydration is the most common serious complication. Signs include tacky gums, loss of skin elasticity, sunken eyes, lethargy, and reduced urine output despite continued dosing. A dog that stops drinking while on furosemide is at high risk. Call your veterinarian the same day. ### Ototoxicity Rapid intravenous injection of furosemide can damage the inner ear and cause hearing loss. This is a known risk of loop diuretics and is the reason injectable furosemide is given slowly over several minutes rather than pushed in as a fast bolus. If your dog is hospitalized and receiving IV furosemide, the veterinary team will control the rate. At home, this risk does not apply to oral dosing. ### When to Call Your Veterinarian Immediately - Resting breathing rate above 30 breaths per minute that does not settle - Collapse, weakness, or inability to stand - Vomiting that prevents the dog from keeping the medication down - Refusal to drink for more than 12 hours - Sudden weight loss of more than 5 percent of body weight - Muscle twitching, head tilt, or apparent hearing loss - Blood in the stool or black tarry stool ## Monitoring on Furosemide Monitoring is not optional. Furosemide can quietly cause electrolyte and kidney problems before a dog looks sick, and the only way to catch them is through bloodwork and weight checks. ### What Gets Checked - **Serum electrolytes**, especially potassium, sodium, and chloride [15][16] - **Renal values**, specifically BUN and creatinine [15][3] - **Hydration status** by physical examination and, in some cases, total plasma protein [14] - **Body weight** at every visit and weekly at home - **Resting respiratory rate and effort** as a marker of congestion [13][2][5] - **Urine sodium** in some specialty settings, as a measure of diuretic responsiveness [2][5][11][10] ### How Often - **Within 24 to 48 hours** of starting furosemide or changing the dose in a hospitalized dog - **At 5 to 7 days** after starting or changing an oral dose in a stable outpatient - **Every 3 to 6 months** once the dog is stable on a fixed dose - **Immediately** if new signs appear, regardless of the schedule A study of dogs with heart failure on captopril, furosemide, a sodium-restricted diet, and digoxin monitored serum electrolytes and renal function for five consecutive weeks in seven dogs and for 17 weeks or longer in six. Two dogs were euthanized after four weeks because of acute decompensation, and one developed severe azotemia [15]. The intensity of that monitoring reflects how quickly things can change in heart failure. ### Home Monitoring Log Keep a simple log with four columns: date, weight, resting breathing rate, and any new signs. Bring it to every recheck. This log often reveals a trend before a single visit can. ## Who Should Not Receive Furosemide Furosemide is not appropriate for every dog. Your veterinarian will weigh the risks in these situations: - **Anuria or severe oliguria**, where the kidneys are not producing urine - **Severe dehydration or hypovolemia** before fluid status is corrected - **Severe electrolyte depletion**, especially low potassium or low sodium, before it is addressed - **Known hypersensitivity to furosemide** - **Dogs already on high doses of other diuretics** without careful reassessment Furosemide is used cautiously in dogs with pre-existing kidney disease, liver disease, or diabetes insipidus. It is also used cautiously in dogs on other drugs that affect electrolytes or kidney blood flow. ### Pregnancy and Nursing Furosemide crosses the placenta and enters milk. It is generally avoided in pregnant or nursing dogs unless the benefit clearly outweighs the risk. Discuss this with your veterinarian if your dog is bred or nursing. ## Drug Interactions Furosemide interacts with several medications commonly used in dogs with heart disease. - **ACE inhibitors** such as enalapril and benazepril. These are standard partners with furosemide in heart failure, and the combination can affect potassium and kidney function. In a study of normal dogs and dogs with heart failure, the combination of captopril, furosemide, and a sodium-restricted diet produced at least one high potassium reading in three of six normal dogs, and one normal dog developed azotemia [15]. This is why electrolytes and renal values are checked after starting or changing either drug. - **Spironolactone**, a potassium-sparing diuretic. Combining it with furosemide can help preserve potassium, but it also raises the risk of hyperkalemia. A large trial of 569 dogs with mitral valve disease and heart failure used a combination of benazepril and spironolactone alongside furosemide and found improved outcomes versus benazepril alone [12]. - **Digoxin.** Furosemide-induced potassium loss increases the risk of digoxin toxicity. Potassium must be watched closely in dogs on both drugs [15]. - **Aminoglycoside antibiotics.** Both drugs can damage the ear, and the combination increases ototoxicity risk. - **NSAIDs.** These reduce kidney blood flow and can blunt furosemide's effect while increasing kidney injury risk. - **Corticosteroids.** These also promote potassium loss and can worsen hypokalemia. Always tell your veterinarian about every medication, supplement, and over-the-counter product your dog receives. ## How Furosemide Compares With Alternatives Furosemide is the first-line loop diuretic for congestive heart failure in dogs. Alternatives and add-ons include: - **Spironolactone**, a potassium-sparing diuretic that works on a different part of the kidney tubule. It is often added to furosemide in heart failure to counteract potassium loss and to block aldosterone [12]. - **Thiazide diuretics**, which act on a different tubule segment. They are sometimes added when furosemide alone is not enough, but this combination requires careful monitoring. - **Torsemide**, another loop diuretic with a longer duration of action. It is used in some dogs when furosemide response is poor. - **Pimobendan**, an inodilator that improves heart function. It is not a diuretic, but it is a standard part of heart failure therapy and often reduces the furosemide dose needed [17][9]. - **ACE inhibitors** such as enalapril and benazepril, which reduce the hormonal drive to retain sodium and water [15][12]. Furosemide remains the fastest and most reliable way to clear fluid from the lungs. No other drug class matches its speed in an acute crisis. ## Questions to Ask Your Veterinarian Bring these to your next appointment: 1. What is the exact dose, route, and frequency for my dog? 2. When should the first recheck bloodwork be done? 3. What resting breathing rate should trigger a call to you? 4. What weight change should worry me? 5. Should I restrict salt in my dog's diet, and if so, how? 6. Are there other heart medications my dog should be on alongside furosemide? 7. What signs of dehydration or low potassium should I watch for? 8. What is the plan if oral furosemide stops working? ## Limitations and When to Contact a Veterinarian Furosemide dosing is individual. Two dogs of the same breed and weight with the same diagnosis can need very different doses, and the right dose changes as heart failure progresses. No article can tell you what your dog needs. Contact your veterinarian promptly if your dog develops any of the following: - Resting breathing rate above 30 breaths per minute - Increased effort to breathe, or breathing with the elbows out - Coughing that worsens or becomes productive - Collapse, weakness, or reluctance to move - Vomiting or diarrhea that lasts more than 24 hours - Refusal to eat or drink - Sudden weight gain or loss - Muscle twitching, head tilt, or apparent hearing loss - Any new medication started by another veterinarian If your dog is struggling to breathe, go to an emergency hospital immediately. Do not wait for a scheduled appointment. ## Frequently Asked Questions ### What is furosemide used for in dogs? Furosemide is a prescription loop diuretic used to remove excess fluid from the lungs and body in dogs with congestive heart failure and edema. It is the first-line drug for pulmonary edema caused by left-sided heart failure. ### What is the usual furosemide dose for dogs? The label-sourced range is 1 to 2 mg/kg given by injection into a vein, muscle, or under the skin, or 1 to 4 mg/kg by mouth every 8 to 12 hours. Your veterinarian will set the exact dose for your dog. ### How long does furosemide take to work in dogs? Injectable furosemide begins working within minutes. Oral furosemide starts working within about an hour, and the effect lasts roughly 6 to 8 hours per dose. ### Can I give my dog furosemide without a prescription? No. Furosemide is prescription-only in the United States. Giving a diuretic without veterinary supervision can cause dehydration, electrolyte imbalance, or kidney injury. ### What are the most common side effects of furosemide in dogs? Increased urination and thirst are expected. More serious effects include dehydration, low potassium, low sodium, low chloride, and kidney injury. Rapid intravenous injection can damage hearing. ### How often should my dog's bloodwork be checked on furosemide? Bloodwork is typically checked within 24 to 48 hours of a dose change in hospital, at 5 to 7 days after starting or changing an oral dose, and every 3 to 6 months once stable. Your veterinarian may check more often. ### Can furosemide be stopped once my dog feels better? Furosemide is usually continued long term because it controls fluid but does not cure the underlying heart disease. In rare cases, dogs with mitral valve disease have stabilized enough to taper or stop the drug, but this is a veterinary decision based on repeat examinations and imaging. ### What should I do if my dog vomits after taking furosemide? Call your veterinarian. A single vomit may not be serious, but repeated vomiting can mean the drug is not being absorbed, and it can also cause further electrolyte loss. Do not give another dose until you have spoken with your veterinarian. ## Related Articles - [Cat Prednisolone for Allergies: Side Effects and Safe Use](/knowledge/veterinary-medicine/skin-allergy-and-ear-care/cat-prednisolone-allergies) - [Dog Prednisone for Allergies: Side Effects and Safe Use](/knowledge/veterinary-medicine/skin-allergy-and-ear-care/dog-prednisone-allergies) - [Prednisone for Dogs: Uses, Side Effects, and Safety Guidelines](/knowledge/veterinary-medicine/preventive-care/prednisone-for-dogs-uses-side-effects-and-safety-guidelines) - [What Are the Side Effects of Gabapentin for Cats?](/knowledge/veterinary-medicine/pet-medication-guide/gabapentin-side-effects-cats) - [What Are the Side Effects of Clavamox for Dogs?](/knowledge/veterinary-medicine/pet-medication-guide/clavamox-side-effects-dogs) - [What Are the Side Effects of Apoquel for Cats?](/knowledge/veterinary-medicine/pet-medication-guide/apoquel-side-effects-cats) ## Sources 1. [Diuretics for Use in Animals - Pharmacology - Merck Veterinary Manual](https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-cardiovascular-system/diuretics-for-use-in-animals) 2. [Urine sodium concentration after intravenous furosemide in dogs with acute congestive heart failure and correlation with treatment efficacy.](https://pubmed.ncbi.nlm.nih.gov/38038223/) 3. [Retrospective evaluation of risk factors for development of kidney injury after parenteral furosemide treatment of left-sided congestive heart failure in dogs.](https://pubmed.ncbi.nlm.nih.gov/36254646/) 4. [Radiographic lung congestion scores in dogs with acute congestive heart failure caused by myxomatous mitral valve disease.](https://pubmed.ncbi.nlm.nih.gov/37694988/) 5. [Spot urinary electrolytes are associated with decongestion and duration of hospitalization in dogs with acute left-sided congestive heart failure secondary to myxomatous mitral valve disease.](https://pubmed.ncbi.nlm.nih.gov/42385769/) 6. [Predictors of reoccurrence of congestive signs within 180 days after successful treatment of the first episode of congestive heart failure in dogs with myxomatous mitral valve disease.](https://pubmed.ncbi.nlm.nih.gov/33706221/) 7. [Neutrophil-to-lymphocyte ratio is increased in dogs with acute congestive heart failure secondary to myxomatous mitral valve disease compared to both dogs with heart murmurs and healthy controls.](https://pubmed.ncbi.nlm.nih.gov/37406992/) 8. [Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure.](https://pubmed.ncbi.nlm.nih.gov/33741312/) 9. [Survival and echocardiographic data in dogs with congestive heart failure caused by mitral valve disease and treated by multiple drugs: a retrospective study of 21 cases.](https://pubmed.ncbi.nlm.nih.gov/22547843/) 10. [Toward quantification of loop diuretic responsiveness for congestive heart failure.](https://pubmed.ncbi.nlm.nih.gov/36408832/) 11. [Urine sodium concentration and diuretic responsiveness in dogs receiving orally administered loop diuretics for chronic congestive heart failure.](https://pubmed.ncbi.nlm.nih.gov/42302767/) 12. [Clinical efficacy of a benazepril and spironolactone combination in dogs with congestive heart failure due to myxomatous mitral valve disease: The BEnazepril Spironolactone STudy (BESST).](https://pubmed.ncbi.nlm.nih.gov/34028078/) 13. [Subcutaneous Furosemide Therapy for Chronic Management of Refractory Congestive Heart Failure in Dogs and Cats.](https://pubmed.ncbi.nlm.nih.gov/39943128/) 14. [Constant rate infusion vs. intermittent bolus administration of IV furosemide in 100 pets with acute left-sided congestive heart failure: A retrospective study.](https://pubmed.ncbi.nlm.nih.gov/30103918/) 15. [The effect of combined therapy with captopril, furosemide, and a sodium-restricted diet on serum electrolyte concentrations and renal function in normal dogs and dogs with congestive heart failure.](https://pubmed.ncbi.nlm.nih.gov/7837109/) 16. [Clinical relevance of serum electrolytes in dogs and cats with acute heart failure: A retrospective study.](https://pubmed.ncbi.nlm.nih.gov/34096660/) 17. [Changes in hepatic and renal Doppler ultrasonography: Current standard therapy in dogs with congestive heart failure.](https://pubmed.ncbi.nlm.nih.gov/41200353/)