# Gabapentin Cat Dose: Pain and Anxiety Dose and Monitoring ## Key Takeaways - Gabapentin is indicated for both neuropathic pain and situational/chronic anxiety in cats, with distinct dosing strategies for each. For situational anxiety, a single dose of 100 mg per cat (approx. 13-30 mg/kg) administered 90-120 minutes prior to a stressful event is supported by clinical trials. - For chronic pain management, particularly neuropathic or musculoskeletal pain, lower doses of 5-10 mg/kg every 8-12 hours are commonly employed, with studies showing efficacy at an average of 6.5 mg/kg every 12 hours for extended periods. - Gabapentin's mechanism involves binding to the alpha-2-delta subunit of voltage-gated calcium channels, reducing excitatory neurotransmitter release, and it exhibits high oral bioavailability (approx. 78.71%) with a half-life of about 5.6 hours in cats. - Common adverse effects include dose-dependent sedation and ataxia, which are generally transient; however, gabapentin can significantly alter neurologic examination findings, including proprioceptive deficits. - Cats with chronic kidney disease (CKD) require dose reduction and careful monitoring due to impaired renal excretion, leading to higher and prolonged serum concentrations, with a single 10 mg/kg dose studied for anxiolysis in this population. - The human oral solution formulation of gabapentin must be avoided due to the presence of xylitol, a toxic substance for cats; veterinary-compounded suspensions are recommended for accurate dosing, especially for chronic use. --- Gabapentin is one of the most frequently prescribed medications in feline practice, valued for its dual role in managing neuropathic pain and situational anxiety. For a [cat](/knowledge/veterinary-medicine/clinical-methods/cat) owner, the most common question is straightforward: "What dose do I give my cat?" The answer depends on the indication, the cat's health status, and the desired effect. For situational anxiety, a single dose of 100 mg per cat (roughly 13 to 30 mg/kg) administered 90 minutes to 2 hours before a stressful event is well supported by clinical trials [1][2]. For chronic pain, particularly neuropathic or musculoskeletal pain, lower doses such as 5 to 10 mg/kg every 8 to 12 hours are commonly used, with long-term studies showing efficacy at an average of 6.5 mg/kg every 12 hours [3][4]. This article provides a definitive, source-grounded review of gabapentin dosing, monitoring, and safety in cats. **Owner Triage Summary:** If your veterinarian has prescribed gabapentin, give the exact dose and timing they provided. Do not adjust the dose without veterinary guidance. If your cat has kidney disease, is very old, or is on other sedatives, the dose may need to be reduced. Watch for sedation, ataxia (wobbliness), and increased affection. Seek immediate veterinary care if your cat collapses, has difficulty breathing, or shows signs of an allergic reaction. --- ## At a Glance: Gabapentin Dosing in Cats The following table summarizes common dosing strategies from peer-reviewed studies. This is a clinical reference, not a substitute for a veterinarian's prescription. | Indication | Common Dose | Timing | Key Evidence | | :--- | :--- | :--- | :--- | | **Situational Anxiety / Vet Visit** | 100 mg per cat (approx. 13–30 mg/kg) | 90 minutes to 2 hours before the event | [1][2] | | **Anxiety (Hyperthyroid Cats)** | 20 mg/kg | 1 hour before leaving home | [5] | | **Pre-Surgical Stress (OVH)** | 20 mg/kg | 2–4 hours before anesthesia | [6] | | **Neuropathic Pain (e.g., Feline Orofacial Pain, Post-Surgical)** | 8 mg/kg every 12 hours | Ongoing | [7] | | **Chronic Musculoskeletal Pain / Trauma** | Average 6.5 mg/kg every 12 hours | Ongoing, months | [3] | | **Acute Pain (Thermal Antinociception)** | 5–30 mg/kg (single dose) | Peak effect at 1–2 hours | [4] | | **CKD (Chronic Kidney Disease)** | 10 mg/kg (single dose) | 3 hours before exam; monitor for sedation | [8][9] | --- ## Understanding Gabapentin: Mechanism and Clinical Use Gabapentin is a structural analogue of the neurotransmitter gamma-aminobutyric acid (GABA). Despite its name, it does not bind directly to GABA receptors. Instead, it binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding reduces the release of excitatory neurotransmitters, which is thought to underlie its analgesic, anticonvulsant, and anxiolytic properties [10][11]. In cats, gabapentin is highly bioavailable. A 2025 pharmacokinetic study showed that oral bioavailability is approximately 78.71% ± 18.55%. After an oral dose of 25 mg/kg, peak plasma concentration (Cmax) of 13.94 ± 3.75 µg/mL is reached in about 1.83 hours (Tmax), with a half-life of 5.60 hours [11]. This pharmacokinetic profile supports its use as a pre-appointment medication, as peak behavioral effects often coincide with peak plasma concentrations. --- ## Gabapentin for Anxiety and Stress in Cats ### Pre-Veterinary Visit Anxiolysis The most robust evidence for gabapentin in cats is for reducing stress and fear-based aggression during veterinary examinations. A landmark randomized, blinded, crossover trial by van Haaften et al. (2017) evaluated 20 healthy pet cats with a history of fractious behavior. Owners administered 100 mg of gabapentin (13.0 to 29.4 mg/kg) or a placebo 90 minutes before transport. The study found that owner-assessed stress scores during transportation and examination, as well as veterinarian-assessed compliance scores, were significantly better when cats received gabapentin [2]. Similarly, Kruszka et al. (2021) studied 55 cats, 26 of which had a history of fear-based aggressive behaviors. Cats received either 100 mg or 200 mg of gabapentin or a placebo 2 hours before a standardized 9-step clinical exam. Compliance scores were significantly higher after gabapentin administration (median score 9) compared to placebo (median score 0.5), meaning most cats allowed the full examination protocol [1]. **Dosing for Anxiety:** The most common effective dose is 100 mg per cat, regardless of body weight, which translates to a wide mg/kg range depending on the cat's size [1][2]. For larger or more anxious cats, 200 mg may be used [1]. A 2022 study in hyperthyroid cats used a weight-based dose of 20 mg/kg, administered 1 hour before departure, and found significant improvements in transport stress and compliance scores compared to placebo [5]. ### Use in Shelter and Community Cats Gabapentin's anxiolytic effects extend to shelter and community cats. In a study of cats undergoing ovariohysterectomy (OVH), a 20 mg/kg dose of liquid gabapentin was administered 2 to 4 hours prior to anesthesia. While this study did not find a significant difference in stress scores between the gabapentin and placebo groups, it is important to note that both groups received standard premedication and the study population was healthy, young shelter cats [6]. In contrast, a field trial by Pankratz et al. (2018) evaluated single-dose oral gabapentin (50 mg or 100 mg) in cage-trap confined community cats presented for trap-neuter-return (TNR). Cat stress scores were significantly lower in cats receiving gabapentin compared to placebo, with the greatest reduction observed at 2 hours post-treatment. Importantly, there was no difference in sedation scores between groups, suggesting that gabapentin reduced fear without causing profound immobility, which is crucial for the safety of community cats [12]. ### Comparison with Other Anxiolytics Gabapentin is often compared to other oral anxiolytics like trazodone. A 2025 study compared the effects of oral single-dose trazodone (50 mg), gabapentin (100 mg), and a combination of both in healthy cats. The study found that the trazodone-gabapentin combination produced the highest sedation scores but also caused a reduction in heart rate and short-duration excitatory reactions in 37.5% of cats. Gabapentin alone provided anxiolysis with fewer cardiovascular effects [13]. This suggests that while combination therapy can be more potent, it carries a higher risk of adverse effects and should be reserved for cases where monotherapy is insufficient. --- ## Gabapentin for Pain Management in Cats ### Neuropathic and Chronic Pain Gabapentin is a cornerstone in the management of chronic and neuropathic pain in cats, conditions that are often challenging to treat. The 2015 AAHA/AAFP Pain Management Guidelines and the 2022 WSAVA Guidelines for the Recognition, Assessment, and Treatment of Pain both acknowledge the role of gabapentin in multi-modal analgesia [7]. A case series by Lorenz et al. (2013) detailed the long-term use of gabapentin in three cats with musculoskeletal disease or head trauma. The cats received gabapentin for several months at an average dose of 6.5 mg/kg every 12 hours. Clinical signs suggestive of pain, such as aggression, avoiding human interaction, and loss of appetite, decreased with administration. Owners reported satisfactory pain management and no obvious side effects during the treatment period [3]. Another case report described the use of a compounded gabapentin suspension (8 mg/kg every 12 hours) in an older cat with suspected lumbosacral intervertebral disk disease. This case is notable because the commercially available tablets could not be accurately split for the cat's dose, and the manufactured solution (Neurontin) contains xylitol, which is toxic to cats. A compounded suspension provided a safe and effective alternative [14]. ### Acute Pain and Antinociception Pypendop et al. (2010) conducted a rigorous experimental study to determine the thermal antinociceptive effect of orally administered gabapentin in healthy cats. They administered single doses of 5, 10, or 30 mg/kg. While all doses increased the thermal threshold (the temperature at which the cat withdrew from a thermal probe), the effect was not statistically significant compared to placebo in this small study (n=6). However, the study did confirm that gabapentin is absorbed and reaches peak plasma concentrations between 60 and 120 minutes after administration [4]. This study highlights that gabapentin is not a potent standalone analgesic for acute, severe pain but may be a valuable adjunct. ### Post-Surgical and Trauma-Related Pain In the context of post-surgical neuropathic pain, gabapentin is often used in combination with other analgesics. A 2024 case report described a cat with chronic, self-traumatic skin lesions caused by post-surgical neuropathic pain. The treatment protocol included gabapentin (8 mg/kg every 12 hours for 60 days) alongside prednisone, amitriptyline, and ketamine. The combination resulted in significant improvement of the lesions and cessation of intense itching within four hours of starting treatment [7]. This underscores the importance of gabapentin as part of a multimodal, rather than monomodal, approach to complex pain. --- ## Monitoring Gabapentin Therapy ### Onset and Duration of Action Understanding the pharmacokinetics of gabapentin is essential for monitoring. After oral administration, peak plasma concentrations are reached in 1 to 2 hours [11][4]. The clinical effects, such as sedation and anxiolysis, are typically observed within this window. The half-life is approximately 5.6 hours, meaning that with chronic dosing (every 8 to 12 hours), steady-state concentrations are achieved within 1 to 2 days [11]. ### Behavioral and Physical Monitoring Owners and veterinarians should monitor for the following effects: - **Sedation:** This is the most common side effect. Cats may appear drowsy or sleepier than usual. In a study of pre-appointment gabapentin, sedation was common, and ataxia (wobbliness) was also reported [2]. A 2025 systematic review confirmed that gabapentin has dose-dependent sedative effects [10]. - **Ataxia:** A wobbly, uncoordinated gait is frequently observed, especially at higher doses. This is typically transient and resolves as the drug is metabolized [2][15]. - **Increased Affection:** Some cats become unusually relaxed and affectionate, which is often a desired effect for veterinary visits. - **Gastrointestinal Signs:** Hypersalivation (drooling) and vomiting have been reported, particularly if the capsule is bitter or if the cat is stressed [2][12]. - **Neurologic Examination Changes:** This is a critical point for veterinarians. Gabapentin can cause significant changes in the neurologic examination. A 2023 study found that a single 100 mg dose caused proprioceptive ataxia, paw placement deficits, and hopping deficits in a significant number of healthy cats [16]. A 2024 study confirmed these findings, noting that 50% of young and geriatric cats exhibited an increase in their overall neurologic examination score post-gabapentin, mainly through new or progressive postural reaction deficits and gait changes [15]. ### Cardiovascular and Respiratory Monitoring Gabapentin has a wide safety margin regarding cardiovascular function. A 2022 study using echocardiography found no difference in heart rate, respiratory rate, or systolic blood pressure in healthy cats after a single 100 mg dose of gabapentin [17]. Another study on the trazodone-gabapentin combination found that gabapentin alone had minimal impact on cardiovascular variables, though the combination did reduce heart rate [13]. A 2025 systematic review concluded that gabapentin ensures an anxiolytic effect without altering any cardiovascular, echocardiographic, or hemodynamic aspects [10]. However, a 2024 study specifically focused on blood pressure in cats with and without chronic kidney disease (CKD) found that a single 10 mg/kg dose of gabapentin significantly lowered systolic blood pressure compared to placebo. The median blood pressure was 122 mmHg after gabapentin versus 150 mmHg after placebo. This effect was seen in both healthy cats and those with CKD [8]. This is an important consideration, as a lower blood pressure reading could mask hypertension in a stressed cat or cause clinical signs of hypotension in a compromised patient. ### Special Populations: Cats with Chronic Kidney Disease Gabapentin is primarily eliminated by the kidneys. Therefore, cats with CKD have significantly higher serum concentrations of the drug. A 2022 pharmacokinetic study found that cats with CKD had significantly higher dose-normalized serum gabapentin concentrations at 3 and 8 hours post-administration compared to healthy cats. These concentrations were correlated with serum creatinine levels [9]. **Clinical Implication:** In cats with CKD, the dose of gabapentin should be reduced, and the dosing interval may need to be extended. A single dose of 10 mg/kg has been studied and shown to be effective for anxiolysis, but it may cause more profound or prolonged sedation in these patients [8][9]. Owners of CKD cats should be counseled to monitor for excessive sedation and ataxia. --- ## Safety, Contraindications, and Adverse Effects ### General Safety Profile Gabapentin has a wide therapeutic index in cats. The most common adverse effects are sedation and ataxia, which are generally mild and self-limiting [10][2]. In shelter cats, no adverse effects were detected specific to gabapentin administration [12]. ### Contraindications and Precautions - **Hypersensitivity:** Cats with a known allergy to gabapentin or pregabalin should not receive it. - **Severe Renal Disease:** As gabapentin is renally excreted, cats with advanced CKD (IRIS stage 3 or 4) should receive lower doses, and the dosing interval should be increased [9]. - **Concurrent Sedatives:** Gabapentin can potentiate the effects of other central nervous system depressants, such as opioids, benzodiazepines, and dexmedetomidine. In a study of cats sedated with dexmedetomidine, prior administration of gabapentin (100 mg) resulted in higher sedation scores and lower propofol requirements for anesthetic induction [18]. This is beneficial for anesthesia but requires careful dose adjustment of anesthetic agents. - **Pregnancy and Lactation:** The safety of gabapentin in pregnant or lactating queens has not been fully established. Use with caution. ### Drug Interactions - **Antacids:** Antacids containing aluminum or magnesium can reduce the absorption of gabapentin. It is recommended to separate dosing by at least 2 hours. - **Hydrocodone:** Gabapentin may increase the serum concentration of hydrocodone. - **Other Sedatives:** As mentioned, the sedative effects of gabapentin are additive with other CNS depressants [13][18]. ### Toxicity and Overdose Gabapentin overdose is rarely fatal in cats. Signs of overdose include profound sedation, ataxia, and lethargy. In severe cases, respiratory depression may occur. There is no specific antidote; treatment is supportive, including intravenous fluids and monitoring of vital signs. --- ## Gabapentin Formulations and Compounding Gabapentin is available in several formulations, but this can be a source of confusion and risk for cat owners. - **Human Tablets/Capsules:** These are widely available in doses of 100 mg, 300 mg, 400 mg, 600 mg, and 800 mg. The 100 mg capsule is the most commonly used for cats. However, splitting a 300 mg tablet to get a 100 mg dose is inaccurate and can lead to dosing errors [14]. - **Human Oral Solution (Neurontin):** This is a significant hazard. The commercial oral solution contains xylitol, a sugar substitute that is highly toxic to cats, causing rapid insulin release, hypoglycemia, liver failure, and death. This formulation must never be used in cats [14]. - **Compounded Suspensions:** Veterinary compounding pharmacies can create a palatable liquid suspension of gabapentin in flavors like chicken or fish. This is often the best option for accurate dosing in cats, especially for small doses or long-term use. The case report on lower back pain in an older cat specifically highlighted the need for a compounded suspension due to the inability to accurately split tablets and the toxicity of the manufactured solution [14]. --- ## Practical Dosing Strategies and Owner Instructions ### For Situational Anxiety (Vet Visits, Travel) 1. **Dose:** 100 mg per cat (or 20 mg/kg if weight-based). For very large or highly anxious cats, 200 mg may be considered [1][2][5]. 2. **Timing:** Administer 90 minutes to 2 hours before the anticipated stressful event [1][2]. For hyperthyroid cats, 1 hour before leaving home was effective [5]. 3. **Administration:** Give the medication with a small amount of food or a treat to reduce the risk of hypersalivation and vomiting [10]. 4. **Monitoring:** Expect mild to moderate sedation. Your cat may be wobbly. This is normal and should resolve within 8 to 12 hours. ### For Chronic Pain Management 1. **Dose:** Start low, typically 5 to 10 mg/kg every 8 to 12 hours. The dose can be titrated up by your veterinarian based on response and side effects [3][4]. 2. **Timing:** Give the medication at consistent times each day. 3. **Administration:** Use a compounded suspension for accurate dosing if tablets cannot be split [14]. 4. **Monitoring:** It may take several days to see the full analgesic effect. Monitor for improvements in activity, appetite, and sociability. Report any signs of excessive sedation or ataxia to your veterinarian. ### The "Gabapentin Holiday" and Tapering Gabapentin should not be stopped abruptly after long-term use, as this can lead to withdrawal-like symptoms such as anxiety, tremors, or seizures. Your veterinarian will provide a tapering schedule to gradually reduce the dose over several days to weeks. --- ## Limitations and When to Contact a Veterinarian This article provides a comprehensive overview of gabapentin dosing and monitoring based on peer-reviewed literature. However, it cannot predict individual responses. Breed, age, and concurrent disease can significantly alter how a cat metabolizes and responds to gabapentin. For example, a 2024 study noted that geriatric cats may have more significant changes in anxiety and sedation scores compared to younger cats [15]. The specific dose for your cat must be determined by a veterinarian who has performed a physical examination and understands your cat's complete medical history. **Contact your veterinarian immediately if you observe any of the following:** - **Severe Sedation:** Your cat is difficult to rouse or unresponsive. - **Respiratory Distress:** Labored breathing, panting, or blue-tinged gums. - **Severe Ataxia:** Your cat is unable to stand or walk. - **Vomiting or Diarrhea:** Persistent or severe gastrointestinal upset. - **Signs of an Allergic Reaction:** Facial swelling, hives, or sudden onset of itching. --- ## Frequently Asked Questions ### 1. How much gabapentin can I give my cat for anxiety? For situational anxiety, a dose of 100 mg per cat (approximately 13 to 30 mg/kg) given 90 minutes to 2 hours before the stressful event is the most evidence-based dose [1][2]. ### 2. How long does it take for gabapentin to work in cats? Gabapentin reaches peak plasma concentrations in 1 to 2 hours after oral administration, and clinical effects like sedation and anxiolysis are typically seen within this window [11][4]. ### 3. Can I give my cat human gabapentin capsules? Yes, 100 mg human capsules are commonly used. However, you must never use the human oral solution (Neurontin) because it contains xylitol, which is toxic to cats [14]. ### 4. Is gabapentin safe for cats with kidney disease? Gabapentin should be used with caution in cats with chronic kidney disease (CKD). Because it is eliminated by the kidneys, drug concentrations are higher and last longer. A lower dose, such as 10 mg/kg, is often used, and cats should be monitored for prolonged sedation [8][9]. ### 5. What are the common side effects of gabapentin in cats? The most common side effects are sedation and ataxia (wobbliness). Hypersalivation and vomiting can also occur, especially if the capsule is bitter or the cat is stressed [2][12]. ### 6. Can gabapentin be used for long-term pain management in cats? Yes. Long-term use of gabapentin has been shown to be beneficial for controlling chronic musculoskeletal pain and neuropathic pain in cats, with an average dose of 6.5 mg/kg every 12 hours used for several months [3]. ### 7. Will gabapentin affect my cat's neurological examination? Yes. Gabapentin can cause significant changes in the neurological examination, including proprioceptive ataxia, paw placement deficits, and hopping deficits. It is important to inform your veterinarian if your cat has recently received gabapentin before a neurologic exam [15][16]. ### 8. Can I give my cat gabapentin and trazodone together? While the combination of gabapentin and trazodone produces higher sedation scores, it also carries a higher risk of cardiovascular effects and excitatory reactions. This combination should only be used under the direct supervision of a veterinarian [13]. --- ## Limitations and When to Contact a Veterinarian This article serves as an educational resource and does not replace professional veterinary advice. The information provided, including specific dosages, is derived from clinical studies and case reports. However, every cat is an individual. Breed-specific sensitivities, underlying health conditions, and concurrent medications can all influence the safety and efficacy of gabapentin. The dosing information in this article cannot predict how a specific breed or individual cat will respond. Always consult with your veterinarian to determine the appropriate dose and monitoring plan for your cat. If you have any concerns about your cat's health or medication, contact your veterinary clinic immediately. --- ## Frequently Asked Questions ### What is the standard gabapentin dose for a cat before a vet visit? The standard dose for pre-vet visit anxiety is 100 mg per cat, given 90 minutes to 2 hours before the appointment [1][2]. ### How quickly does gabapentin take effect in cats? Gabapentin typically takes effect within 1 to 2 hours, as peak blood levels are reached in that time frame [11]. ### Is it safe to use liquid gabapentin made for humans in cats? No, the commercial human liquid formulation contains xylitol, which is toxic to cats. A veterinary-compounded liquid is safe [14]. ### What should I do if my cat is too sleepy after gabapentin? Mild to moderate sedation is expected. Keep your cat in a safe, quiet space. If the sedation is severe, contact your veterinarian. ### Can a cat with chronic kidney disease take gabapentin? Yes, but at a reduced dose and with careful monitoring, as the drug accumulates in the body due to decreased renal clearance [9]. ### Does gabapentin cause wobbliness in cats? Yes, ataxia is a common side effect, especially at higher doses. It is usually temporary [2][15]. ### Can I give my cat gabapentin every day for pain? Yes, for chronic pain, gabapentin is often given every 8 to 12 hours, sometimes for months at a time [7][3]. ### Are there any serious side effects of gabapentin in cats? Serious side effects are rare but can include severe sedation, respiratory depression, and allergic reactions. Seek immediate veterinary care if these occur. --- This article is educational and is not a substitute for veterinary diagnosis or treatment. Always consult your veterinarian for any health concerns or before administering any medication. ## Sources [1] [Clinical evaluation of the effects of a single oral dose of gabapentin on fear-based aggressive behaviors in cats during veterinary examinations.](https://pubmed.ncbi.nlm.nih.gov/34727056/) [2] [Effects of a single preappointment dose of gabapentin on signs of stress in cats during transportation and veterinary examination.](https://pubmed.ncbi.nlm.nih.gov/29099247/) [3] [Long-term use of gabapentin for musculoskeletal disease and trauma in three cats.](https://pubmed.ncbi.nlm.nih.gov/23253881/) [4] [Thermal antinociceptive effect of orally administered gabapentin in healthy cats.](https://pubmed.ncbi.nlm.nih.gov/20807141/) [5] [Randomised clinical trial evaluating the effect of a single preappointment dose of gabapentin on signs of stress in hyperthyroid cats.](https://pubmed.ncbi.nlm.nih.gov/35481442/) [6] [Evaluation of the effects of gabapentin on stress and pain in shelter cats undergoing ovariohysterectomy.](https://pubmed.ncbi.nlm.nih.gov/41534210/) [7] [A combined treatment for self-traumatic chronic skin lesions associated with post-surgical neuropathic pain in a domestic cat: a pharmacological and cold atmospheric plasma approach.](https://pubmed.ncbi.nlm.nih.gov/39133400/) [8] [Assessment of the effect of gabapentin on blood pressure in cats with and without chronic kidney disease.](https://pubmed.ncbi.nlm.nih.gov/38770706/) [9] [Serum concentrations of gabapentin in cats with chronic kidney disease.](https://pubmed.ncbi.nlm.nih.gov/35195476/) [10] [A Systematic Review of the Sedative, Behavioral, Analgesic and Cardiovascular Effects of Gabapentin in Cats.](https://pubmed.ncbi.nlm.nih.gov/41150078/) [11] [Development and Validation of an LC-MS/MS Method for Quantifying Gabapentin in Plasma: Application to a Pharmacokinetic Study in Cats.](https://pubmed.ncbi.nlm.nih.gov/40218342/) [12] [Use of single-dose oral gabapentin to attenuate fear responses in cage-trap confined community cats: a double-blind, placebo-controlled field trial.](https://pubmed.ncbi.nlm.nih.gov/28718700/) [13] [Trazodone-gabapentin association increases sedation scores with mild hemodynamic and echocardiographic impact in healthy cats.](https://pubmed.ncbi.nlm.nih.gov/39701182/) [14] [Compounded gabapentin suspension for lower back pain in an older cat: a case report.](https://pubmed.ncbi.nlm.nih.gov/23965500/) [15] [Evaluation of gabapentin administration on neurologic examination in 2 different age groups of healthy cats.](https://pubmed.ncbi.nlm.nih.gov/39400394/) [16] [Does preappointment gabapentin affect neurological examination findings? A prospective, randomized and blinded study in healthy cats.](https://pubmed.ncbi.nlm.nih.gov/36790148/) [17] [Evaluation of the effects of gabapentin on the physiologic and echocardiographic variables of healthy cats: a prospective, randomized and blinded study.](https://pubmed.ncbi.nlm.nih.gov/36383193/) [18] [Influence of prior administration of gabapentin and integrative practices on sedation scores, physiological parameters, and propofol requirement in cats sedated with dexmedetomidine.](https://pubmed.ncbi.nlm.nih.gov/42437608/) [19] [Effects of using a propofol priming and coinduction with ketamine or S(+) Ketamine on the dose of induction and duration of propofol in cats.](https://pubmed.ncbi.nlm.nih.gov/42035835/) [20] [Infrared Thermography and Physiological Variables as Methods for Recognizing Fear in Domestic Cats (Felis catus) Using Three Pharmacological Models: Cannabidiol, Gabapentin, and Synthetic Facial Pheromones.](https://pubmed.ncbi.nlm.nih.gov/40559760/)

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