# Abyssinian Health Problems: Inherited Conditions and Cardiac Screenings ## Key Takeaways - Abyssinian cats have a documented genetic predisposition to Pyruvate Kinase (PK) Deficiency, an autosomal recessive disorder affecting red blood cells, leading to hemolytic anemia with clinical signs ranging from subclinical to intermittent weakness and jaundice, definitively diagnosed via DNA blood testing. - Progressive Retinal Atrophy (PRA) is another autosomal recessive inherited condition in Abyssinians, characterized by gradual retinal degeneration leading to night blindness and eventual complete blindness, detectable through ophthalmoscopic examination and confirmed by DNA blood testing. - Hypertrophic Cardiomyopathy (HCM) is a significant concern, a polygenic cardiac disease where the left ventricle thickens, often presenting asymptomatically but potentially leading to congestive heart failure or sudden death; definitive diagnosis and screening are achieved through echocardiography. - Proactive veterinary care for Abyssinians includes annual wellness exams with thorough auscultation, and for breeding cats, annual echocardiograms and genetic testing for PK Deficiency and PRA are crucial for early detection and prevention of disease propagation. - Management of PK Deficiency is largely supportive, focusing on minimizing stress and monitoring bloodwork, while PRA management involves environmental adaptation for blindness; HCM management is stage-dependent, ranging from monitoring to pharmacological interventions like diuretics, ACE inhibitors, and pimobendan. - Responsible breeding practices are paramount, emphasizing the use of genetically clear cats for PK Deficiency and PRA, and annual cardiac screening with echocardiography to remove affected individuals from breeding programs, thereby reducing the incidence of these inherited conditions. --- The Abyssinian [cat](/knowledge/veterinary-medicine/clinical-methods/cat) is an ancient and distinctive breed, known for its ticked tabby coat, large almond-shaped eyes, and highly active, social personality. While generally a robust and long-lived breed, the Abyssinian carries a documented predisposition to specific inherited disorders. For any owner or prospective buyer, understanding these breed-specific health problems is not about expecting illness, but about practicing proactive, preventative veterinary care. The two most significant areas of concern are inherited genetic conditions, which can affect red blood cells and vision, and inherited cardiac disease, specifically hypertrophic cardiomyopathy (HCM). This article provides a definitive, source-grounded overview of Abyssinian health, focusing on the inherited conditions that define the breed's health profile and the critical role of cardiac screening. Early detection through genetic testing and regular veterinary check-ups, including echocardiography, is the cornerstone of managing these conditions and ensuring a long, healthy life. If you notice any sudden change in your cat's behavior, breathing, or mobility, contact your veterinarian immediately. ## At a Glance: The Abyssinian Health Profile The following table summarizes the primary inherited health concerns in the Abyssinian breed. This is a clinical guide for discussion with your veterinarian, not a substitute for professional diagnosis. | Condition | System Affected | Inheritance Pattern | Key Clinical Signs | Screening Method | | :--- | :--- | :--- | :--- | :--- | | **Pyruvate Kinase Deficiency (PK Deficiency)** | Red Blood Cells | Autosomal Recessive | Intermittent weakness, lethargy, pale gums, weight loss, possible jaundice. Many cats are subclinical. | DNA Blood Test | | **Progressive Retinal Atrophy (PRA)** | Eyes (Retina) | Autosomal Recessive | Night blindness progressing to complete blindness; pupils may be dilated. | DNA Blood Test; Ophthalmoscopic Exam | | **Hypertrophic Cardiomyopathy (HCM)** | Heart | Polygenic (Complex) | Often asymptomatic; may present with lethargy, rapid breathing, or sudden death. | Echocardiogram (Ultrasound) | | **Patellar Luxation** | Skeletal (Knees) | Suspected Polygenic | Intermittent skipping or hopping of the hind leg, pain. | Orthopedic Examination | ## Understanding Inherited Conditions in the Abyssinian Inherited conditions are diseases caused by mutations in an animal's DNA. In purebred cats like the Abyssinian, certain mutations become more prevalent due to a limited gene pool. Being aware of these conditions allows owners and breeders to make informed decisions through genetic testing, which can significantly reduce the incidence of these diseases in future generations. ### Pyruvate Kinase Deficiency (PK Deficiency) Pyruvate kinase (PK) is a crucial enzyme in red blood cells (erythrocytes) responsible for generating energy. In Abyssinian cats, a specific genetic mutation can lead to a deficiency of this enzyme, a condition known as pyruvate kinase deficiency. This deficiency causes red blood cells to have a shortened lifespan, leading to a condition called hemolytic anemia, where the body destroys its own red blood cells. **Clinical Presentation and Diagnosis** The clinical signs of PK deficiency are highly variable. Many affected cats are described as having "compensated hemolytic anemia," meaning their body produces new red blood cells fast enough to prevent severe clinical signs. These cats may appear completely healthy for much of their lives. However, the disease can also manifest with more obvious signs, including: - Intermittent lethargy and weakness - Pale mucous membranes (gums) - Weight loss - An enlarged spleen (splenomegaly), which can sometimes be felt by a veterinarian - Jaundice (a yellowish tint to the gums, skin, or eyes), indicating significant red blood cell destruction Diagnosis is typically confirmed with a specific DNA test. This test identifies whether a cat is clear (no copies of the mutation), a carrier (one copy of the mutation, typically healthy), or affected (two copies of the mutation). A complete blood count (CBC) can also reveal anemia and characteristic changes in red blood cell shape, but the DNA test is the definitive diagnostic tool for the inherited form. ### Progressive Retinal Atrophy (PRA) Progressive retinal atrophy (PRA) is a group of inherited diseases that cause the gradual degeneration of the retina, the light-sensitive tissue at the back of the eye. In Abyssinians, PRA typically has an early onset, with degeneration beginning as early as one to two years of age, although the progression rate can vary. **Clinical Presentation and Diagnosis** The first sign of PRA is usually night blindness (nyctalopia). An owner might notice the cat hesitating to jump in the dark, bumping into furniture in low light, or seeming more cautious in unfamiliar environments. As the disease progresses, the cat's daytime vision is also affected, eventually leading to complete blindness. Cats adapt remarkably well to blindness, especially in a stable home environment, often relying on their other senses. A veterinary ophthalmologist can diagnose PRA through a thorough eye examination. An ophthalmoscope allows the vet to see the characteristic changes in the retina, such as increased reflectivity and thinning of the blood vessels. However, a DNA test is available for the specific mutation found in Abyssinians and can confirm the diagnosis, often before clinical signs are visible. This is particularly useful for breeders to identify carriers. ### Other Inherited Considerations While PK deficiency and PRA are the most well-known single-gene disorders in the breed, the Abyssinian is also predisposed to other conditions with a suspected or confirmed genetic component. Patellar luxation, where the kneecap slips out of its normal groove, is seen with some frequency in the breed. While the exact inheritance is not fully mapped, it is considered a polygenic condition. Signs include a sudden skip or hop in the hind leg, which may resolve on its own, but chronic cases can lead to arthritis and may require surgical intervention. ## The Critical Role of Cardiac Screenings: Hypertrophic Cardiomyopathy Hypertrophic cardiomyopathy (HCM) is the most common heart disease in cats and is a significant health concern for the Abyssinian breed. HCM is a disease of the heart muscle where the walls of the left ventricle (the main pumping chamber) become abnormally thick. This thickening reduces the heart's ability to relax and fill with blood properly, leading to a cascade of potential complications. ### Pathophysiology of HCM In a normal heart, the left ventricle relaxes to fill with oxygen-rich blood from the lungs and then contracts to pump that blood out to the body. In a cat with HCM, the thickened heart muscle becomes stiff. This stiffness impairs the relaxation phase (diastole), leading to increased pressure within the heart. Over time, this can cause: - **Left Atrial Enlargement:** The left atrium, the chamber that receives blood from the lungs, must work harder to push blood into the stiff ventricle, causing it to enlarge. - **Congestive Heart Failure (CHF):** The increased pressure can back up into the lungs, causing fluid to leak from the blood vessels into the lung tissue (pulmonary edema). This is a life-threatening emergency. - **Arterial Thromboembolism (FATE):** The enlarged left atrium can cause blood to pool and clot. If this clot dislodges, it can travel through the bloodstream and become lodged at the end of the aorta, where it branches to supply the hind legs. This causes sudden, severe hind-leg paralysis and intense pain. - **Sudden Cardiac Death:** In some cases, arrhythmias caused by the diseased heart muscle can lead to sudden, unexpected death. ### Why Screening is Essential The most challenging aspect of HCM is that many affected cats show no clinical signs for years. By the time an owner notices symptoms like lethargy, rapid or labored breathing, or loss of appetite, the disease is often in an advanced stage. This is why proactive cardiac screening is so critical for the breed. **The Gold Standard: Echocardiography** An echocardiogram, or cardiac ultrasound, is the gold standard for diagnosing HCM. This non-invasive imaging technique allows a veterinary cardiologist to visualize the heart's structure in real-time, directly measuring the thickness of the ventricular walls. It can detect even mild thickening, allowing for a diagnosis long before clinical signs appear. Screening recommendations, supported by groups like the American College of Veterinary Internal Medicine (ACVIM), suggest that breeding cats should be screened annually with an echocardiogram. For pet owners, an initial screening can provide a baseline, with follow-up exams recommended based on the cat's age, breed, and the cardiologist's findings. **The Role of Genetic Testing for HCM** Unlike PK deficiency and PRA, which are caused by a single gene mutation, HCM in cats is a polygenic disease. This means multiple genes are involved, and the disease's expression is influenced by other factors. While a genetic test for HCM exists, it is important to understand its limitations. A positive test may indicate an increased risk, but it does not guarantee the cat will develop the disease. Conversely, a negative test does not guarantee the cat will remain free of HCM, as other, unidentified mutations may be present. Therefore, genetic testing for HCM should be viewed as a risk-assessment tool, not a definitive diagnostic test. The echocardiogram remains the definitive screening method. ## Veterinary Examination and Diagnostics A comprehensive approach to Abyssinian health involves regular wellness exams, which are vital for early detection of both inherited and acquired diseases. ### The Annual Wellness Examination At a minimum, an annual wellness exam is recommended for all cats. For Abyssinians, this exam should be particularly thorough. Your veterinarian will: - **Perform a Physical Exam:** This includes listening to the heart and lungs with a stethoscope (auscultation). While a heart murmur can be a sign of HCM, its absence does not rule out the disease. The vet will also check the cat's eyes for any signs of retinal changes and palpate the abdomen to check organ size. - **Discuss Nutrition and Behavior:** Changes in appetite, activity, or behavior can be early indicators of underlying health issues. - **Recommend Baseline Bloodwork:** Routine blood tests can help establish what is normal for your cat and can screen for early signs of kidney disease, hyperthyroidism, or anemia. ### Advanced Diagnostics for Inherited Diseases If you are considering breeding your Abyssinian or if you want a complete health profile, several specific tests are available. - **Genetic Testing:** DNA tests for PK deficiency and PRA are simple blood or cheek swab tests. These are highly recommended for all breeding cats to prevent the propagation of these diseases. Testing for HCM can also be performed, but its results should be interpreted by a veterinarian. - **Echocardiography:** As discussed, this is the definitive test for HCM. It is recommended for all breeding cats annually and for any cat showing clinical signs suggestive of heart disease. - **Ophthalmologic Examination:** A board-certified veterinary ophthalmologist can perform a detailed retinal exam to detect early signs of PRA that a general practitioner might miss. - **Blood Pressure Measurement:** Hypertension (high blood pressure) is common in older cats and can be a secondary issue in cats with kidney disease or hyperthyroidism. It can also cause retinal detachment and sudden blindness. ## Evidence-Based Management and Treatment There is no cure for the inherited conditions described, but they can be managed effectively to maintain a good quality of life. Management strategies are based on the specific disease and its severity. ### Managing PK Deficiency Most cats with PK deficiency do not require any specific treatment and live normal, healthy lives with their compensated anemia. The goal is to minimize stress on the body's red blood cell production. Management may include: - **Nutritional Support:** A high-quality, balanced diet is essential. Some specialists may recommend adding antioxidants like Vitamin E, but this should only be done under veterinary guidance. - **Avoiding Stress:** Stress can trigger a "hemolytic crisis," where the rate of red blood cell destruction outpaces production. Keeping a stable, low-stress environment is beneficial. - **Monitoring:** Regular blood work to monitor the anemia is important. In rare, severe cases, a blood transfusion may be necessary. ### Managing PRA There is no treatment to stop or reverse retinal degeneration. Management focuses on keeping the cat safe and comfortable as vision declines. - **Environmental Stability:** Do not rearrange furniture. Keep food, water, and litter boxes in consistent, accessible locations. - **Safety Proofing:** Block access to stairs, balconies, or pools that could be dangerous for a blind cat. - **Use of Other Senses:** Encourage play using toys that make noise or have strong scents. Your cat will rely heavily on hearing and smell. ### Managing HCM The management of HCM depends on the stage of the disease. The goal is to manage clinical signs, slow disease progression, and prevent complications like heart failure and blood clots. - **Asymptomatic Stage:** Cats diagnosed with early HCM but showing no signs may not require medication. Regular monitoring with an echocardiogram is crucial to track disease progression. - **Clinical Heart Failure:** If a cat develops congestive heart failure, treatment is more intensive and may include: - **Diuretics (e.g., Furosemide):** To remove fluid from the lungs. - **ACE Inhibitors (e.g., Enalapril):** To dilate blood vessels and reduce the workload on the heart. - **Pimobendan:** A positive inotrope that helps the heart muscle contract more effectively and is now a mainstay of HCM treatment in cats. - **Antiplatelet Drugs (e.g., Clopidogrel):** To reduce the risk of blood clot formation. *Note: The specific medications and dosages must be determined by a licensed veterinarian. Never administer any medication to your cat without veterinary supervision.* ## Unsafe Home Remedies and What to Avoid When it comes to serious inherited conditions, there are no safe or effective home remedies. Attempting to treat these diseases without veterinary oversight can be dangerous and delay critical care. - **Do not give human medications:** Drugs like ibuprofen or acetaminophen (paracetamol) are highly toxic to cats and can be fatal. - **Do not alter your cat's diet without veterinary advice:** While a balanced diet is important, making sudden changes can cause gastrointestinal upset. For cats with heart disease, specific nutritional modifications (like sodium restriction) may be recommended, but only by a veterinarian. - **Do not use unproven supplements:** Many supplements claim to support heart or eye health, but their efficacy in treating these specific inherited diseases is unproven. Some can even interfere with prescribed medications. - **Do not delay emergency care:** If your cat is showing signs of respiratory distress (rapid, open-mouth breathing) or sudden hind-leg paralysis, this is a life-threatening emergency. Do not wait to see if it resolves; seek immediate veterinary care. ## Prevention and Breeding Considerations The most powerful tool we have against inherited diseases is prevention through responsible breeding practices. ### The Importance of Genetic Testing For single-gene disorders like PK deficiency and PRA, genetic testing is straightforward and highly effective. - **Clear (N/N):** The cat has no copies of the mutation and will not develop the disease or pass it on. - **Carrier (N/PK or N/PRA):** The cat has one copy of the mutation. It will not develop the disease but can pass the mutation to 50% of its offspring. - **Affected (PK/PK or PRA/PRA):** The cat has two copies of the mutation and will be affected by the disease. The goal of a breeding program should be to eliminate affected kittens. This can be achieved by ensuring that at least one parent in every mating is "clear" of the specific mutation. For example, breeding a clear cat to a carrier will produce no affected kittens, but 50% of the litter will be carriers. Breeding two carriers together is strongly discouraged, as it can produce affected kittens. ### The Role of Cardiac Screening in Breeding Because HCM is polygenic, the approach is different. Breeders should screen all breeding cats with an echocardiogram annually. Cats diagnosed with HCM should be removed from breeding programs. By selecting breeding stock with healthy hearts over successive generations, breeders can gradually reduce the prevalence of the disease in the breed. ## Prognosis and Long-Term Outlook The prognosis for an Abyssinian with an inherited condition varies greatly depending on the specific disease. - **PK Deficiency:** The prognosis is generally excellent. Most affected cats live normal, full lifespans with minimal to no clinical signs. - **PRA:** The prognosis for a good quality of life is good, though the cat will eventually become blind. With a safe and stable environment, blind cats can live very happy, fulfilling lives. - **HCM:** The prognosis is highly variable. Some cats live for years with mild disease and no clinical signs. Others may progress to heart failure or experience sudden death. The average survival time after a diagnosis of congestive heart failure is around 1 to 2 years, but some cats do much better with appropriate treatment. Early detection through screening offers the best chance to manage the disease and prolong life. ## Limitations and When to Contact a Veterinarian This article provides a comprehensive overview of known breed-specific health issues in the Abyssinian. However, it is crucial to understand its limitations. This information cannot predict the future health of any individual cat. An Abyssinian may carry a genetic predisposition for a condition but never develop it, or they may develop a condition not listed here. Breed-level information is a guide for awareness, not a definitive diagnosis. You should contact your veterinarian immediately if you observe any of the following "red flag" signs in your Abyssinian: - **Difficulty Breathing:** Rapid, labored, or open-mouth breathing (dyspnea) is a sign of a potential cardiac emergency or respiratory disease. - **Sudden Hind-Leg Paralysis:** A cat that is suddenly dragging one or both hind legs and is vocalizing in pain may have a blood clot (FATE), a complication of HCM. - **Collapse or Loss of Consciousness:** This could indicate a cardiac arrhythmia or other serious neurological issue. - **Pale or Yellow Gums:** This can indicate severe anemia or liver disease. - **Sudden Blindness:** If your cat suddenly starts bumping into things, it could be due to a rapid progression of PRA, hypertension, or retinal detachment. - **Lethargy and Loss of Appetite:** These are non-specific signs but can indicate a serious underlying illness. Always err on the side of caution. Prompt veterinary attention can be life-saving. ## Frequently Asked Questions ### 1. What is the most common health problem in Abyssinian cats? Hypertrophic cardiomyopathy (HCM) is arguably the most significant health concern in the breed due to its prevalence and potential for sudden death. However, the most commonly *diagnosed* inherited conditions are often PK deficiency and PRA, largely because they can be easily identified through DNA testing. ### 2. How much does an echocardiogram for a cat cost? The cost of an echocardiogram varies widely depending on your geographic location and whether it is performed by a general practitioner or a board-certified veterinary cardiologist. Generally, you can expect to pay anywhere from $300 to $600 or more. ### 3. Can a cat with pyruvate kinase deficiency live a normal life? Yes, absolutely. Many cats with PK deficiency are described as subclinical, meaning they show no outward signs of illness. With regular veterinary monitoring and a low-stress environment, they can live a normal, full lifespan. ### 4. At what age do Abyssinian cats show signs of PRA? The onset of PRA in Abyssinians is variable but is often considered "early-onset," with retinal degeneration sometimes detectable as early as 1 to 2 years of age. However, the progression to noticeable blindness can be slow, and some cats may not show obvious signs until they are older. ### 5. Is a heart murmur always present in cats with HCM? No. A heart murmur is a common finding in cats with HCM, but its absence does not rule out the disease. Some cats with HCM have no audible murmur, while others may have an arrhythmia. An echocardiogram is the only way to definitively diagnose or rule out HCM. ### 6. Should I get my Abyssinian kitten genetically tested? Yes, it is highly recommended. Testing for PK deficiency and PRA is simple and provides valuable information for managing your cat's health and for making responsible breeding decisions if you ever plan to breed. Testing for HCM can also be done, but its results should be interpreted with the understanding that it is not a definitive diagnostic test. ### 7. What are the signs of congestive heart failure in a cat? The most common signs of congestive heart failure in cats are lethargy, decreased appetite, and most notably, increased respiratory effort. You might notice your cat breathing more rapidly while resting (over 30 breaths per minute) or with an open mouth. This is an emergency. ### 8. Are all Abyssinian cats affected by these inherited diseases? No, not at all. While the breed has a higher prevalence of these specific mutations compared to the general cat population, many Abyssinians are clear of these diseases and live their entire lives without ever being affected by them. Responsible breeding practices are actively working to reduce the frequency of these genes. ## Conclusion The Abyssinian is a wonderful, intelligent, and active companion. The key to ensuring a long and healthy life for these cats lies in proactive health management. By understanding the breed's predisposition to inherited conditions like PK deficiency, PRA, and HCM, owners can work with their veterinarians to implement appropriate screening protocols. Genetic testing for single-gene disorders and regular echocardiograms for cardiac health are not just medical procedures; they are essential components of responsible ownership that allow for early intervention, better management, and ultimately, a better quality of life for these remarkable cats. --- **This article is educational and is not a substitute for veterinary diagnosis or treatment.** Always consult with your veterinarian for any health concerns regarding your pet. ## Sources 1. [Gender differences in the prevalence of anxiety and depression and care seeking for mental health problems in Nepal: Analysis of nationally representative survey data](https://www.semanticscholar.org/paper/1d83dbe519b8043cd7501c76b3e39428b3d8af17) 2. [A systematic review of work-related health problems of factory workers in the textile and fashion industry](https://www.semanticscholar.org/paper/ad26a656c5666e365b75a926d4168971adb4534c) 3. [Mental health problems and their related factors among seafarers: a scoping review](https://www.semanticscholar.org/paper/6172ae7117749c79da68975fd3364a759465157a) 4. [Mental Health Problems and Needs among Transitional-Age Youth in Indonesia](https://www.semanticscholar.org/paper/97a0d28f975f02646c1033358e9f35187dfd114d) 5. [The effect of mental and physical health problems on sickness absence](https://www.semanticscholar.org/paper/b8c28d48a924c29ec27f8f28ddef4c040e824019) 6. [Social Prescribing and Lifestyle Medicine—A Remedy to Chronic Health Problems?](https://www.semanticscholar.org/paper/cb93aeea960f01879073992689132a819959f91a) 7. [Internet use and mental health problems among older people in Shanghai, China: the moderating roles of chronic diseases and household income](https://www.semanticscholar.org/paper/046023c28d78996eb2bca0de3f3f81f0d662a109) 8. [Post-migration Social–Environmental Factors Associated with Mental Health Problems Among Asylum Seekers: A Systematic Review](https://www.semanticscholar.org/paper/19f3f0bd589e900253fee885d1ed0a9dd9b230cf) 9. [Risk factors and consequences of mental health problems in nurses: A scoping review of cohort studies.](https://www.semanticscholar.org/paper/b8322836e167e868f4445e2b0eb8fcc10fea7012) 10. [Prevalence of mental health problems in people living with HIV: a systematic review and meta-analysis](https://www.semanticscholar.org/paper/3422f9bfcb82d7bc9f86172854b3dc8e80c3e039) 11. [Assessment of the association between health problems and cooking fuel type, and barriers towards clean cooking among rural household people in Bangladesh](https://www.semanticscholar.org/paper/e8069165d5eb089698a219553cf1af4ae7b0d344) 12. [The Relationship between Social Media and the Increase in Mental Health Problems](https://www.semanticscholar.org/paper/43be4ea979a30b996afdcb74a8d51b80f3ea590c) 13. [Mental Health Is a Family Affair—Systematic Review and Meta-Analysis on the Associations between Mental Health Problems in Parents and Children during the COVID-19 Pandemic](https://www.semanticscholar.org/paper/55c57010ed4e6960a7ab1a3e523b02417c22c5fb) 14. [Investigating the Health Impacts of Climate Change among People with Pre-Existing Mental Health Problems: A Scoping Review](https://www.semanticscholar.org/paper/85d32bbad4c8b0aa95241c2f149e159c2b57dc3a) 15. [Prevalence and predictors of mental health problems in refugee children living in informal settlements in Lebanon](https://www.semanticscholar.org/paper/f763e719bc49952813f43e06082e000dce2b7c27) 16. [Common mental health problems in medical students and junior doctors – an overview of systematic reviews](https://www.semanticscholar.org/paper/351116fe91028e3eb5d56f4dbc8a0363bfd56230) 17. [The relationship between social support and mental health problems during pregnancy: a systematic review and meta-analysis](https://www.semanticscholar.org/paper/8b524c45a1fdc829ef5630933121c51c761566e1) 18. [Mental health problems in children with intellectual disability.](https://www.semanticscholar.org/paper/0e601a5b1a297115d0d793009324fad899124dfa) 19. [Mental Health Problems among Young People—A Scoping Review of Help-Seeking](https://www.semanticscholar.org/paper/086e081f97ba5001142ccb3025d8f6deb5e83a5f) 20. [Childhood adversities and mental health problems: A systematic review](https://www.semanticscholar.org/paper/c9e251a3141dddb2dc9eda486e17da7793afd88a) ## Related Clinical & Scientific Guides * [Birman Health Problems: Inherited Conditions and Cardiac Screenings](/knowledge/veterinary-medicine/breed-specific-health/birman-health-problems-inherited-conditions-and-cardiac-screenings) * [Singapura Cat Health Problems: Inherited Conditions and Cardiac Screenings](/knowledge/veterinary-medicine/breed-specific-health/singapura-cat-health-problems-inherited-conditions-and-cardiac-screenings) * [Siberian Cat Health Problems: Inherited Conditions and Cardiac Screenings](/knowledge/veterinary-medicine/breed-specific-health/siberian-cat-health-problems-inherited-conditions-and-cardiac-screenings)